SnapShot: The ESCRT Machinery
نویسندگان
چکیده
منابع مشابه
The ESCRT machinery: new roles at new holes
The ESCRT machinery drives a diverse collection of membrane remodeling events, including multivesicular body biogenesis, release of enveloped retroviruses and both reformation of the nuclear envelope and cytokinetic abscission during mitotic exit. These events share the requirement for a topologically equivalent membrane remodeling for their completion and the cells deployment of the ESCRT mach...
متن کاملThe ESCRT machinery: new functions in viral and cellular biology.
The ESCRT (endosomal sorting complex required for transport) machinery consists of a number of cytosolic proteins that make up three functional subcomplexes: ESCRT-I, ESCRT-II and ESCRT-III. These proteins function in multivesicular body formation and cell division and are co-opted by enveloped retroviruses to facilitate viral egress. Analysis of these functions may help illuminate conserved me...
متن کاملThe ESCRT machinery at a glance.
This article is part of a Minifocus on the ESCRT machinery. For further reading, please see related articles: ‘No strings attached: the ESCRT machinery in viral budding and cytokinesis’ by Bethan McDonald and Juan Martin-Serrano (J. Cell Sci. 122, 2167-2177) and ‘How do ESCRT proteins control autophagy?’ by Tor Erik Rusten and Harald Stenmark (J. Cell Sci. 122, 2179-2183). The endosomal sorting...
متن کاملFunctional interplay between a virus and the ESCRT machinery in archaea.
Recently it has been discovered that a number of eukaryotic viruses, including HIV, coopt the cellular Endosomal Sorting Complex Required for Transport (ESCRT) machinery to affect egress from infected cells. Strikingly, the ESCRT apparatus is conserved in a subset of Archaea, including members of the genus Sulfolobus where it plays a role in cytokinesis. In the current work, we reveal that the ...
متن کاملMembrane manipulations by the ESCRT machinery
The endosomal sorting complexes required for transport (ESCRTs) collectively comprise a machinery that was first known for its function in the degradation of transmembrane proteins in the endocytic pathway of eukaryotic cells. Since their discovery, however, ESCRTs have been recognized as playing important roles at the plasma membrane, which appears to be the original site of function for the E...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Cell
دوره 137 شماره
صفحات -
تاریخ انتشار 2009